For example, hematopoietic stem cells found in the bone marrow only differentiate into cells of peripheral blood. These generate specialized cells for their location, mostly to maintain cell numbers or replenish dying cells. They are isolated mostly from abnormal and/or supernumerary preimplantation embryos that are produced during in vitro fertilization treatments and donated afterwards for ESC research purposes, with the informed consent of the donor.Īlso known as somatic stem cells, these multipotent stem cells are located in small quantities in specific “stem cell niches” found in many organs in the adult human body. Stem cells are classified into two broad types according to their source:ĮSCs are pluripotent stem cells that are able to form all adult cell types and are obtained from the inner cell mass (ICM) of a 5-6 day old human blastocyst. They can differentiate only into myogenic precursor cells. Muscle satellite cells found in the adult muscle are unipotent.
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